Actos Now for the prevention of diabetes (ACT NOW) study

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Actos Now for the prevention of diabetes (ACT NOW) study

BACKGROUND Impaired glucose tolerance (IGT) is a prediabetic state. If IGT can be prevented from progressing to overt diabetes, hyperglycemia-related complications can be avoided. The purpose of the present study was to examine whether pioglitazone (ACTOS) can prevent progression of IGT to type 2 diabetes mellitus (T2DM) in a prospective randomized, double blind, placebo controlled trial. MET...

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Prevention of Diabetes With Pioglitazone in ACT NOW

We examined the metabolic characteristics that attend the development of type 2 diabetes (T2DM) in 441 impaired glucose tolerance (IGT) subjects who participated in the ACT NOW Study and had complete end-of-study metabolic measurements. Subjects were randomized to receive pioglitazone (PGZ; 45 mg/day) or placebo and were observed for a median of 2.4 years. Indices of insulin sensitivity (Matsud...

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ژورنال

عنوان ژورنال: BMC Endocrine Disorders

سال: 2009

ISSN: 1472-6823

DOI: 10.1186/1472-6823-9-17